John Maraganore Net Worth (Updated 2026).

John Maraganore, a name that has become synonymous with biotechnology innovation, began his career in the early 1990s. Fresh out of Stanford University with a Ph.D. in Biochemistry, Maraganore joined the fledgling biotech industry, drawn by its promise to revolutionize healthcare. He started at a small startup, quickly rising through the ranks due to his exceptional scientific acumen and business savvy.

Maraganore’s big break came in 1996 when he co-founded Alnylam Pharmaceuticals, a company dedicated to developing therapies based on RNA interference, a groundbreaking technology that could silence disease-causing genes. Under his leadership as CEO, Alnylam grew from a tiny startup into a global biopharmaceutical company, becoming the first to bring an RNAi-based medicine to market, Onpattro, in 2018. This marked a significant milestone in medical history and cemented Maraganore’s status as a biotech pioneer.

John Maraganore’s Current Net Worth

As of 2025, John Maraganore’s current net worth is estimated to be around $500 million, according to the latest available information.

John Maraganore’s Career

John Maraganore is a prominent figure in the biotechnology industry, currently serving as the CEO of Alnylam Pharmaceuticals. He has held this position since the company’s inception in 2002. Prior to Alnylam, Maraganore worked at Biogen, where he held various leadership roles over 14 years.

John Maraganore’s Other Ventures

In addition to his role at Alnylam, Maraganore serves on the boards of several other biotechnology companies, including Moderna and BlueRock Therapeutics. He is also a member of the Massachusetts Biotechnology Council’s Board of Directors.

John Maraganore’s Assets

Maraganore’s assets primarily consist of his stake in Alnylam Pharmaceuticals, which has significantly appreciated over the years due to the company’s success. He also owns a substantial portfolio of stocks in other biotechnology companies. Additionally, he owns several properties, including a residence in Massachusetts.

John Maraganore’s Annual Income

In 2020, Maraganore’s total compensation from Alnylam was $17.5 million, which includes his base salary, stock awards, and other compensation. This figure can vary year to year based on the company’s performance and Maraganore’s role in its success.

Frequently Asked Questions about  John Maraganore

John Maraganore Net Worth FAQs

1. What is John Maraganore’s net worth?

John Maraganore’s net worth is estimated to be around $500 million.

2. How did John Maraganore make his fortune?

John Maraganore made his fortune through his successful career in the biotechnology industry. He is the former CEO and current Executive Chairman of Alnylam Pharmaceuticals, a company he co-founded in 2002.

3. What is Alnylam Pharmaceuticals?

Alnylam Pharmaceuticals is a biopharmaceutical company that develops and commercializes medicines based on RNA interference (RNAi). It was founded by John Maraganore in 2002 and he served as its CEO until 2020.

4. What is RNA interference (RNAi)?

RNA interference (RNAi) is a mechanism that cells use to silence genes. It’s a natural process where small RNA molecules, known as microRNAs, bind to complementary RNA sequences, preventing them from being translated into proteins.

5. What are some of Alnylam’s most successful drugs?

Alnylam’s most successful drugs include Onpattro (patisiran), which was approved by the FDA in 2018 for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR), and Givlaari (olipudase alfa), approved in 2020 for the treatment of acid sphingomyelinase deficiency (ASMD).

6. What is John Maraganore’s role at Alnylam now?

After stepping down as CEO in 2020, John Maraganore became the Executive Chairman of Alnylam Pharmaceuticals. In this role, he continues to provide strategic guidance and leadership to the company.

7. What other companies has John Maraganore been involved with?

Before co-founding Alnylam, John Maraganore held various leadership positions at other biotechnology companies, including Biogen and Millennium Pharmaceuticals. He has also served on the boards of several other biotechnology companies.

8. What is John Maraganore’s educational background?

John Maraganore received his Ph.D. in Biochemistry from the University of California, San Diego, and his B.S. in Biochemistry from the University of Notre Dame.

9. What awards has John Maraganore received?

John Maraganore has received several awards and recognitions for his contributions to the biotechnology industry, including the Biotech Hall of Fame Award in 2019 and the PhRMA CEO of the Year Award in 2018.

10. What is John Maraganore’s philanthropic work like?

John Maraganore is known for his philanthropic work, particularly in the areas of education and healthcare. He has been a significant donor to his alma mater, the University of Notre Dame, and has also supported various healthcare initiatives and organizations.