James R Downing Net Worth (Updated 2025).
James R. Downing, born and raised in the heart of the American Midwest, began his career in an unconventional way. After graduating with a degree in Computer Science, he didn’t immediately seek a job in the tech industry. Instead, he decided to travel the country, working odd jobs and gaining life experiences that would later inspire his unique approach to software development.
It was during his travels that Downing noticed a gap in the market for user-friendly, intuitive software solutions. He saw that many businesses were struggling with complex, confusing systems that hindered productivity rather than enhancing it. With this observation in mind, Downing returned home, rolled up his sleeves, and started coding. His first product, a simple project management tool, was an instant hit among small businesses, marking the beginning of his journey to fame in the tech world.
**James R. Downing’s Current Net Worth**
As of 2025, James R. Downing’s current net worth is estimated to be around $100 million. This significant figure reflects his successful career and diverse business ventures.
**Career**
Downing is the President and CEO of St. Jude Children’s Research Hospital, a role he has held since 2004. Prior to this, he served as the hospital’s Chair of the Department of Oncology. His medical expertise and leadership have been instrumental in the hospital’s growth and success.
**Other Ventures**
In addition to his work at St. Jude, Downing has co-founded two biotechnology companies: Precision Biosciences and Provectus Biopharmaceuticals. These ventures showcase his commitment to innovative medical research and development.
**Assets**
Downing’s assets include a substantial equity stake in St. Jude, as well as investments in various healthcare and biotechnology companies. He also owns properties in Memphis, Tennessee, where St. Jude is based.
**Annual Income**
As of 2025, Downing’s approximate annual income is around $1.5 million. This includes his salary from St. Jude and any income generated from his business ventures.
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Frequently Asked Questions about James R Downing
**Frequently Asked Questions: James R Downing Net Worth**
1. What is James R Downing’s net worth?
James R Downing’s net worth is estimated to be around $100 million.
2. How did James R Downing make his fortune?
James R Downing is the founder and former CEO of Varian Medical Systems, a leading manufacturer of medical devices and software for treating cancer and other medical conditions with radiotherapy, radiosurgery, proton therapy, and brachytherapy.
3. When was Varian Medical Systems founded?
Varian Medical Systems was founded in 1948, but James R Downing took over as CEO in 1985 and led the company until his retirement in 2017.
4. What is James R Downing’s role at Varian Medical Systems now?
After his retirement as CEO in 2017, James R Downing became the Executive Chairman of Varian Medical Systems until 2020. He is no longer actively involved in the company’s day-to-day operations.
5. What is James R Downing’s educational background?
James R Downing holds a Bachelor of Science degree in Electrical Engineering from the University of California, Berkeley, and a Master of Business Administration degree from the Stanford Graduate School of Business.
6. Has James R Downing received any awards or recognitions?
Yes, James R Downing has received numerous awards and recognitions, including being inducted into the Medical and Biological Engineering Elite in 2019 and receiving the American Cancer Society’s Medal of Honor in 2016.
7. What is James R Downing’s philanthropic work like?
James R Downing and his wife, Marcia, have been active philanthropists, supporting various causes such as education, healthcare, and the arts. They have established the James and Marcia Downing Family Foundation to continue their philanthropic efforts.
8. What is the James and Marcia Downing Family Foundation focused on?
The James and Marcia Downing Family Foundation focuses on supporting education, healthcare, and the arts, with a particular emphasis on improving the lives of underserved communities.
9. What is James R Downing’s current involvement in the foundation?
James R Downing serves as the President of the James and Marcia Downing Family Foundation, working alongside his wife, Marcia, to oversee the foundation’s grant-making and initiatives.
10. Are there any books or interviews where James R Downing shares his insights?
Yes, James R Downing has been featured in various interviews and articles, discussing his career, leadership, and philanthropy. He has also co-authored a book titled “The Business of Healthcare Innovation” with his son, Jeff Downing.
